Head-to-head
Aggregate
All meetings
| Date | Home | Score | Away | R | Tournament |
|---|---|---|---|---|---|
| 23 Jun 2024 | Uruguay | 3–1 | Panama | H | ITL · Copa América |
| 11 Jun 2022 | Uruguay | 5–0 | Panama | H | ITL · Friendly |
| 07 Jun 2019 | Uruguay | 3–0 | Panama | H | ITL · Friendly |
| 06 Apr 1952 | Panama | 1–6 | Uruguay | A | ITL · Pan American Championship |